生物医学工程
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叶旻
特任副研究员
叶旻,中国科学技术大学特任副研究员,主要从事器官制造、再生医学前沿交叉研究:通过生物制造技术研究仿生血管网络的设计、制备及仿生血管的新生机制研究;人工卵巢构建的关键科学和技术问题;血管化组织细胞培养及神经-血管-生殖类器官的互联互作研究。目前在国内外重要学术期刊发表期刊论文9篇,授权专利2项。
工作经历:
2023/03-至今,中国科大苏州高等研究院,特任副研究员
2020/09-2023/03,清华大学机械系:生物制造中心,博士后助理研究员
学习经历
2013/09-2020/06,清华大学医学院,博士,生物学
2009/09-2013/06,武汉大学生命科学学院,学士
电子邮箱
电子邮箱:min_ye@ustc.edu.cn
主要科研项目
1. 国家重点基础研究发展计划,原始生殖细胞分化体系的建立和功能验证,2018.04 - 2022.12,参加
2. 国家重大科学研究项目,多能干细胞向生殖细胞分化模型及调控机制,2012.01 – 2016.08,参加
3. 国家自然科学基金面上项目,定向分化人类胚胎干细胞为卵子,2012.01 – 2015.12,参加
主要学术论文
1. Ye, Min; Shan, Yiran; Lu, Bingchuan; Luo, Hao; Li, Binhan; Zhang, Yanmei; Wang, Zixuan; Guo, Yuzhi; Ouyang, Liliang; Gu, Jin; Xiong, Zhuo*; Zhang, Ting*. Creating a semi-opened micro-cavity ovary through sacrificial microspheres as an in vitro model for discovering the potential effect of ovarian toxic agents, Bioactive Materials, 2023, 26: 216-230
2. Lu, Bingchuan; Ye, Min; Xia, Jingjing; Zhang, Zhenrui; Xiong, Zhuo*; Zhang, Ting*. Electrical stimulation promotes the vascularization and functionalization of an engineered biomimetic human cardiac tissue. Advanced Healthcare Materials, 2023
3. Fang, Yongcong; Guo, Yihan; Wu, Bingyan; Liu, Zibo; Ye, Min; Xu, Yuanyuan; Ji, Mengke; Chen, Li; Lu, Bingchuan; Nie, Kaiji; Wang, Zixuan; Luo, Jianbin; Zhang, Ting; Sun, Wei; Xiong, Zhuo*. Expanding Embedded 3D Bioprinting Capability for Engineering Complex Organs with Freeform Vascular Networks, Advanced Materials, 2023
4. Ye, Min#; Lu, Bingchuan#; Zhang, Xinyun#; Li, Binhan; Xiong, Zhuo; Zhang, Ting*. Coaxial Embedded Printing of Gelatin Methacryloyl–Alginate Double Network Hydrogel for Multilayer Vascular Tubes, Chinese Journal of Mechanical Engineering: Additive Manufacturing Frontiers, 2022, 1(2): 100024
5. Liu, Yubing#; Lu, Xinmei#; Ye, Min#; Wang, Ling; Tang, Rongxin; Yang, Zhiyong; Turathum, Bongkoch; Liu, Chenchen; Xue, Yujing; Wu, Menghua; Yang, Yannan; Gao, Ermeng; Zhang, Di; Yang, Feng; Kee, Keh-Kooi; Huang, Xingxu; Li, Guanglei*; Chian, Ri-Cheng*. Efficient silencing of the multicopy DUX4 gene by ABE-mediated start codon mutation in human embryos, J Genet Genomics, 2022, 49(10): 982-985
6. Yang, Zhiyong; Ye, Min; Xing, Yaxin; Xie, Qigui; Zhou, Jianhong; Qi, Xinrui; Kee, Kehkooi; Chian, Richeng*. Changes in the Mitochondria-Related Nuclear Gene Expression Profile during Human Oocyte Maturation by the IVM Technique, Cells, 2022, 11(2): 297
7. Ye, Min#; Yang, Zhiyong#; Zhang, Yu; Xing, Yaxin; Xie, Qigui; Zhou, Jianhong; Wang, Ling; Xie, Wei; Kee, KehKooi*; Chian, Richeng*. Single-cell multiomic analysis of in vivo and in vitro matured human oocytes, Human Reproduction, 2020, 35(4): 886-900
8. Jung, Dajung#; Xiong, Jie#; Ye, Min#; Qin, Xunsi#; Li, Lin; Cheng, Shunfeng; Luo, Mengyuan; Peng, Jia; Dong, Ji; Tang, Fuchou; Shen, Wei; Matzuk, Martin M.; Kee, Kehkooi*. In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells, Nature Communications, 2017, 8(1): 15680
9. Guo, Jianying; Ma, Dacheng; Huang, Rujin; Ming, Jia; Ye, Min; Kee, Kehkooi; Xie, Zhen; Na, Jie*. An inducible CRISPR-ON system for controllable gene activation in human pluripotent stem cells, Protein & Cell, 2017, 8(5): 379-393
专利发明
1. 叶旻; 张婷; 熊卓; 鲁冰川; 骆浩; 一种可排卵的人工卵巢支架及其制备方法和应用, 2022-11-22, 中国, ZL202210248677.1
2. 纪家葵; 叶旻; 将人源胚胎干细胞体外诱导为卵泡的方法及其所用培养基, 2017-5-24, 中国, ZL201710373412.3