生物医学工程
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储开芹
特任研究员、博士生导师
储开芹,特任研究员,博士生导师。于1995年获得南开大学物理学士学位,2002年获得上海交通大学物理硕士学位,2009年获得美国罗切斯特大学光学博士学位,随后在加州大学戴维斯分校从事博士后及项目科学家。2015年9月至2021年12月在中国科学技术大学精密机械与精密仪器系担任特任研究员。之后作为特任研究员在中科大苏州高研院工作,主要研究方向是针对活细胞及模式生物观察和分析的多模式高时空分辨显微技术和便携式生物医疗仪器。
电子邮箱:kqchu@ustc.edu.cn
主要研究方向: 无标记高时空分辨显微技术
近5年内学术论文:
1. R Shi#, Y Sun, J Fang, X Chen, ZJ Smith*, K Chu*, Asymmetrical illumination enables lipid droplets segmentation in Caenorhabditis elegans using epi-illumination dark field microscopy, Frontiers in Physics, in press, 2022.
2. Y Dai#, Y Yu#, X Wang, Z Jiang, K Chu, ZJ Smith*, Recent Progress in Label-Free Techniques for Characterization of Extracellular Vesicle Heteorgeneity, 中国科学:化学, in press, 2022. (in Chinese)
3. Y Ma#, T Dai, Y Lei, J Zheng, M Liu, B Sui, ZJ Smith, K Chu*, L Kong*, G Peng*, Label-Free Imaging of Intracellular Organelle Dynamics Using Flat-Fielding Quantitative Phase Contrast Microscopy (FF-QPCM), Optics Express, 30(6), 9505-9520, 2022.
4. Y Pan#, S Guo, ZJ Smith*, K Chu*, Simultaneous 3D deconvolution and halo removal for spatial light interference microscopy through a two-edge apodized Wiener filter, JOSA A, 39(2), 287-296, 2022.
5. R Shi#, X Chen, J Hou, S Guo, ZJ Smith*, K Chu*, Epi-illumination dark field microscopy enables direct visualization of unlabeled small organisms with high spatial and temporal resolution, Journal of Biophotonics, 15(1), e202100185, 2022.
6. S Guo#, Y Ma, Y Pan, ZJ Smith*, K Chu*, Organelle-specific phase contrast microscopy enables gentle monitoring and analysis of mitochondrial network dynamics, Biomedical Optics Express, 12(7), 4363-4379, 2021.
7. P Gao*#, Y Ma, K Wen, M Liu, J Zheng, K Chu, ZJ Smith, L Liu, Recent Advances in Structured Illumination Microscopy, J Phys Photonics, 3, 024009, 2021.
8. X Chen#, P Luo, C Hu, S Yan, D Lu, Y Li, K Chu, ZJ Smith*, Nanometer precise red blood cell sizing using a cost-effective quantitative dark field imaging system, Biomedical Optics Express, 11(10), 5950-5966, 2020.
9. X Wang#, C Hu#, K Chu, ZJ Smith*, Low Resolution Raman: The impact of spectral resolution on limit of detection and imaging speed in hyperspectral imaging, Analyst, 145, 6607, 2020.
10. Q Meng#, T Xu, ZJ Smith, K Chu*, Optical volumetric projection with large NA objectives for fast high-resolution 3D imaging of neural signals, Biomedical Optics Express, 11(7), 3769-3782 (2020).
11. Y Pan#, T Ma, Q Meng, Y Mao, K Chu, Y Men, T Pan, B Li*, J Chu, Droplet digital PCR enabled by microfluidic impact printing for absolute gene quantification, Talanta, 92(7), 5585-5594, 2020.
12. Y Dai#, S Bai#, C Hu, K Chu, B Shen*, ZJ Smith*, Combined morpho-chemical profiling of individual extracellular vesicles and functional nanoparticles without labels, Analytical Chemistry, 92(7), 5585-5594, 2020.
13. Y Li#, X Ma, W Wang, S Yan, F Liu, K Chu, G Xu, ZJ Smith*, Improving the limit of detection in portable luminescent assay readers through smart optical design, Journal of Biophotonics 13(1), e201900241, 2020.
14. Y Ma#, S Guo#, Y Pan,, R Fan, ZJ Smith, S Lane, K Chu*, Quantitative Phase Microscopy with Enhanced Contrast and Improved Resolution through Ultra‐Oblique Illumination (UO‐QPM), Journal of Biophotonics, 12(10), e201900011, 2019.
15. Y Li#, R Zheng#, Y Wu, K Chu, Q Xu*, M Sun*, ZJ Smith*, A low‐cost, automated parasite diagnostic system via a portable, robotic microscope and deep learning, Journal of Biophotonics, 12(9), e201800410, 2019.
16. C Xiao#, ZJ Smith, K Chu*, Simultaneous recovery of both bright and dim structures from noisy fluorescence microscopy images using a modified TV constraint, Journal of Microscopy, 275(11), 24-35, 2019.
17. L Tong#, J Kauer, X Chen, K Chu, H Dou*, ZJ Smith*, Screening of nutritional and genetic anemias using elastic light scattering, Lab on a Chip, 18, 3263-3271, 2018. Q Lu#, G Liu, C Xiao, C Hu, S Zhang, RX Xu, K Chu, Q Xu*, ZJ Smith*, A modular, open-source, slide-scanning microscope for diagnostic applications in resource-constrained settings, PLOS ONE, 13(3), e0194063, 2018.
18. B Cai, X Zhai, Z Wang, Y Shen, RX Xu, ZJ Smith, Q Wen*, K Chu*, Optical volumetric projection for fast 3D imaging through circularly symmetric pupil engineering, Biomedical Optics Express, 9 (2), 437-446, 2018.
19. Y Ma, D Li, ZJ Smith, D Li*, K Chu*, Structured illumination microscopy with inter‐leaved reconstruction (SIMILR), Journal of Biophotonics, 11(2), e201700090, 2018.
20. D Xie, Y Xie, P Liu, L Tong, C Hu, P Shao, K Chu*, ZJ Smith*, Performance of a cost‐effective and automated blood counting system for resource‐limited settings operated by trained and untrained users, Journal of Biophotonics, 11(2), e201700030, 2018.