Dr. Zhengyu Deng is currently a professor at the Suzhou Institute for Advanced Research, University of Science and Technology of China (USTC). His research interests include polymeric biomaterials, degradable polymers, and stimuli-responsive nanoassemblies. He has published over 30 peer-reviewed papers in SCI journals, including Nat. Chem., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Prog. Polym. Sci., JACS Au, and ACS Mater. Lett.
Group website: https://www.x-mol.com/groups/Deng-Zhengyu?lang=en
Email: zydeng@ustc.edu.cn
Professional experience:
2024/07-now, Suzhou Institute for Advanced Study, USTC, Professor
2021/3-2024/06, University of Western Ontario, Postdoctoral Associate, Supervisor: Prof. E. R. Gillies
2017/6-2019/09, Hunan University, Postdoctoral Fellow, Supervisor: Prof. Weihong Tan
Education
2011/09-2017/03, University of Science and Technology of China (USTC), PhD, Supervisor: Prof. Shiyong Liu
2007/09-2011/06, Northwestern Polytechnical University, B.E.
Research directions:
Responsive Biomaterials, Precision Materials, Sustainable Polymers, Bioorthogonal Chemistry
Selected Publications
1. Deng, Z.; Gillies, E. R.* "Self-Immolative Polymers Derived from Renewable Resources via Thiol−Ene Chemistry", Angew. Chem. Int. Ed. 2024, e202420054e.
2. Cen, J.#; Liu, W.#; Xu, J.#; Wang, X.; Zhang, J.; Zhang, J.; Deng, Z.*; Zhou, C.*; Hu, J.*; Liu, S.* "Single-Component High-Resolution Dual-Tone EUV Photoresists Based on Precision Self-Immolative Polymers", Angew. Chem. Int. Ed. 2024, 63, e202415588.
3. Deng, Z.; Liang, X.; Gillies, E. R.* "Click to Self-immolation: A “Click” Functionalization Strategy towards Triggerable Self-Immolative Homopolymers and Block Copolymers", Angew. Chem. Int. Ed. 2024, 63, e202317063 (Hot Paper).
4. Tan, J.#; Deng, Z.#; Song, C.; Xu J.; Zhang, Y.; Yu, Y.; Hu, J.*; Liu, S.* "Coordinating External and Built-In Triggers for Tunable Degradation of Polymeric Nanoparticles via Cycle Amplification", J. Am. Chem. Soc. 2021, 143, 13738.
5. Yang, Q.#; Deng, Z.#; Wang, D.; He, J.; Zhang, D.; Tan, Y.; Peng, T.; Wang, X. Q.*; Tan, W.* "Conjugating Aptamer and Mitomycin C with Reductant-Responsive Linker Leading to Synergistically Enhanced Anticancer Effect", J. Am. Chem. Soc. 2020, 142, 2532.
6. Deng, Z.; Yuan, S.; Xu, X. R.; Liang, H.; Liu, S.* "Reduction-Triggered Transformation of Disulfide-Containing Micelles at Chemically Tunable Rates", Angew. Chem. Int. Ed. 2018, 57, 8896.
7. Deng, Z.; Qian, Y.; Yu, Y.; Liu, G.; Hu, J.; Zhang, G.; Liu, S.* "Engineering Intracellular Delivery Nanocarriers and Nanoreactors from Oxidation-Responsive Polymersomes via Synchronized Bilayer Cross-Linking and Permeabilizing Inside Live Cells", J. Am. Chem. Soc. 2016, 138, 10452 (ESI Highly Cited Papers).
8. Deng, Z.; Gillies, E. R.* "Emerging Trends in the Chemistry of End-to-End Depolymerization", JACS Au 2023, 3, 2436.
9. Shi, Q.#; Deng, Z.#; Hou, M.#; Hu X.*; Liu S.* "Engineering precise sequence-defined polymers for advanced functions", Prog. Polym. Sci. 2023, 141, 101677.
