Dr. Dongfang Wang obtained his PhD degree in Shanghai Institute of Applied Physics, University of Chinese Science Academy in 2014. From August 2014 to July 2022, he engaged in postdoctoral research at the Technical University of Braunschweig in Germany and Emory University in the United States. In August 2022, he joined the Department of Life Sciences and Medicine of the University of Science and Technology of China and the Suzhou Institute for Advanced Study. The main research directions are DNA nanotechnology and the biomedical applications. The structural properties of the DNA molecule are used to realize different molecular self-assembly methodologies, to construct various complex DNA nanostructures, and to apply them to biomedical research.
Email: dongfang_wang@ustc.edu.cn
Professional experience:
2022.08 to present, Suzhou Institute for Advanced Study, USTC, tenure-track professor
2017.12 to 2022.07, Emory University, postdoc
2014.08 to 2017.10, Technical University of Braunschweig, postdoc
Education:
2009.08 to 2014.07, Shanghai Institute of Applied Physics, PhD
2004.09 to 2009.07, Dalian medical university, Bachelor
Research directions:
1. DNA self-assembly methodologies and mechanisms.
2. Single-molecule fluorescence techniques for biophysics and DNA nanotechnology
Publications:
1.Dongfang Wang#, Lei Yu#, Chao-Min Huang, Gaurav Arya, Shuai Chang*, Yonggang Ke* Programmable Transformations of DNA Origami Made of Small Modular Dynamic Units J. Am. Chem. Soc. 2021, 143, 5, 2256–2263.
2.Dongfang Wang, Lei Yu, Bin Ji, Shuai Chang*, Jie Song*, Yonggang Ke* Programming the Curvatures in Reconfigurable DNA Domino Origami by Using Asymmetric Units Nano Lett. 2020, 20, 11, 8236–8241.
3.Sisi Fan#, Dr. Dongfang Wang#, Jin Cheng, Yan Liu, Tao Luo, Prof. Daxiang Cui, Prof. Yonggang Ke, Prof. Jie Song* Information Coding in a Reconfigurable DNA Origami Domino Array. Angewandte Chemie. 2020, 132, 13091-13097.
4.Sisi Fan, Jin Cheng, Yan Liu, Dongfang Wang*, Tao Luo, Bin Dai, Chuan Zhang, Daxiang Cui, Yonggang Ke*, Jie Song* Proximity-Induced Pattern Operations in Reconfigurable DNA Origami Domino Array J. Am. Chem. Soc. 2020, 142, 34, 14566–14573.
5.Sisi Fan#, Dongfang Wang#, Jin Cheng, Jie Song* Create nanoscale patterns with DNA origami. Small. 2019, 15, 1805554.
6.Dongfang Wang#, Jie Song#*, Pengfei Wang, Victor Pan, Yingwei Zhang, Daxiang Cui*, Yonggang Ke* Design and operation of reconfigurable two-dimensional DNA molecular arrays. Nature Protocols. 2018, 13, 2312-2329.
7.Dongfang Wang, Carolin Vietz, Tim Schröder, Birka Lalkens, Guillermo Acuna, Philip Tinnefeld*. A DNA walker as fluorescence signal amplifier. Nano Lett. 2017, 17 (9), pp 5368–5374.
8.Jing Su#, Dongfang Wang#, Lena Nörbel, Jianlei Shen, Zhihan Zhao, Yanzhi Dou, Tianhuan Peng, Jiye Shi, Sanjay Mathur, Chunhai Fan, and Shiping Song*. Multicolor Gold-Silver Nano-Mushrooms as Ready-to-Use SERS Probes for Ultrasensitive and Multiplex DNA/miRNA Detection. Analytical Chemistry. 2017, 89 (4), 2531–2538.
9.Dongfang Wang, Yanming Fu, Juan Yan, Bin Zhao, Bin Dai, Jie Chao, Huajie Liu, Dannong He, Yi Zhang, Shiping Song*, Chunhai Fan. Molecular Logic Gates on DNA Origami nanostructures for MicroRNA Diagnostics. Analytical Chemistry. 2014, 86 (4), pp 1932–1936.
